Sterile Aqueous Injection For Excretory Urography Cerebral Angiography Peripheral Angiography Aortography Intraosseous Venography Direct Cholangiography Hysterosalpingography Splenoportography NOT FOR INTRATHECAL USE
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چکیده
The 50 percent (w/v) solution contains 300 mg iodine per mL and 0.8 mEq (18.1 mg) sodium per mL. It has an osmolality of 1515 mosm/kg (determined by VPO), and is hypertonic to blood. As a point of information only, a 10 percent solution (w/v) is isotonic. The viscosity (cp) is about 3.25 at 25° C and 2.34 at 37° C. Sodium carbonate and hydrochloric acid have been added to adjust pH between 6.5 and 7.7.The pKa is 3.4 for diatrizoic acid. If a solution of this medium is chilled, crystals may form but readily dissolve if the vial is placed in moderately hot water before use; cool to body temperature before injecting.
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